Mar 31, 2012

Singapore - Researchers set heart on studying cardiac death among Asians


SINGAPORE - A first-of-its-kind study in the region will see investigators across 10 countries working together to understand the patterns of survival and death among Asian patients with heart failure.

The five-year study will gather and analyse data on sudden cardiac death in heart failure, with the long-term goal of improving the survival of Asian patients with heart failure.

Funded with a S$5.5-million grant by medical devices company Boston Scientific, the study will focus specifically on 5,000 patients aged 18 and above across the Asia-Pacific region.

The 10 countries involved are: Singapore, Hong Kong, Thailand, Korea, China, Indonesia, Malaysia, the Philippines, India and Japan. In Singapore, six medical centres will participate in the study.

The findings of this study could help doctors better understand the causes of death among Asian patients with heart failure, and determine if such deaths may be prevented with the implantation of cardiac defibrillators.

Studies within the Western populations have shown that sudden cardiac death accounts for 50 per cent of deaths in heart failure and that sudden cardiac death is preventable in some patients by implanting a cardiac defibrillator.

In Asia, however, there is a lack of knowledge of the epidemiology of sudden cardiac death and ignorance regarding the risk of sudden death associated with heart failure.

Associate Professor Carolyn Lam of the National University Heart Centre of Singapore, who leads the study, said there is "an urgent need to fill the knowledge gaps regarding the mortality burden of this disease" and "understand the barriers that prevent quick and easy access to potentially life-saving devices".

The World Health Organization has projected that Asia has the largest increase in cardiovascular disease due to the increasing rates of smoking, obesity, dyslipidemia and diabetes among Asians.

A local study on congestive heart failure among elderly patients, conducted between 1991 to 1998, showed that heart failure admission rose by more than 40 per cent over the last decade, making it the most common cardiac cause of hospitalisation. It also found that the five-year survival rate in patients with heart failure is 32 per cent.

Amanda Lee
todayonline.com



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