Nov 28, 2011

Vietnam - Hepatitis B on rise among pregnant Vietnamese women



The incidence of hepatitis B virus (HBV) among pregnant women in Vietnam has been increasing in recent years and timely detection is necessary to prevent it from being transmitted from mothers to newborns, says a health expert.

Dr Ngo Minh Xuan, Chairman of the Prenatal and Neonatal Association of HCM City (PaNaH), said at a conference on Saturday that it was very important that pregnant women get themselves screened for HBV in the first sixth months of pregnancy.

The conference dealt with issues on healthcare for mothers and infants.

Women could be infected with HBV before or at any phase during pregnancy, Xuan said, adding between 80 and 90 per cent of pregnant women infected with the virus did not display hepatitis symptoms.
He said 90 per cent of newborns infected with HBV from their mothers carried a high risk of contracting chronic hepatitis and liver cancer before they are 10 years old.

He advised pregnant women with chronic hepatitis to use specialised drugs for hepatitis treatment like Lamivudine in the latter half of their pregnancy to try and prevent prenatal HBV transmission.

Hepatitis B was one of the world's most common and serious infectious diseases, he said.
If pregnant women were found out to be infected with HBV early through the screening process, active steps can be taken to prevent the virus from being transmitted to the their newborns by having them vaccinated at birth, he said.

This method helped 80 per cent of neonates worldwide from having HBV transmitted through their mothers, he said.

Xuan advised that newborns of HBV-carrying mothers should receive hepatitis B vaccine within 24 hours of delivery in order to interrupt transmission after delivery.

They should be given the second dose of the vaccine when the infant is a month old, and two remaining doses administered over the next two months.

Nearly 400 million people are chronic carriers of HBV worldwide, and the virus is the leading cause of hepatocellular carcinoma (liver cancer) and cirrhosis, according to the World Health Organisation (WHO).
WHO also estimates that around two million people die due to this disease every year.

In Vietnam alone, nearly 12 million people were currently infected with HBV. Among them, the rate of pregnant women was 10-15 per cent, Xuan said.

Many HBV-carrying mothers are worried about the influence of the mode of delivery (natural, C-section and other methods) and breastfeeding on HBV transmission to their newborns, French doctor Philippe Condominas said.

Research shows that the mode of delivery did not have significant effect on HBV transmission, he added.
Breastfeeding posed no additional risk for transmission from HBV-carrying mothers to their neonates because mother's milk contained antibodies including immunoglobulines and lactoferrines, he said.

It is advisable for pregnant women with chronic hepatitis to have amniocentesis (the testing of amniotic fluid for genetic abnormalities in the fetus) done to check their health.

The amniocentesis procedure was safe and carried very low risk of the foetus getting infected with HBV, Condominas said.

Pregnancy would change the HBsAg and HBeAg status in women infected with hepatitis, so they should have their health tested again after delivery.

The conference, organised by PaNaH in co-operation with Tu Du Obstetrics Hospital under the sponsorship of Humana Vietnam Co Ltd, attracted the participation of more than 300 paediatricians from HCM City and neighbouring provinces.

The News Desk in Ho Chi Minh/Viet Nam News | ANN



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